"Data from the clinical trial also showed that ATC
was especially effective when used with two existing marketed HIV drugs."
HIV integrase:
Since the approval of Merck’s raltegravir (Isentress®), which targets HIV integrase, this drug has been widely
prescribed and has demonstrated itself to be a most effective therapy for HIV infections in combination with an
optimised background regimen. In 2010 Isentress® generated global revenues of around US$1Bn.
"Avexa has discovered a number of novel compound classes with activity superior to raltegravir against wild
type HIV-1. Moreover, these compounds are highly potent against raltegravir- and elvitegravir-resistant
viruses."
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