Brilliant work again Dave, your time and effortaround this topic is a credit to you.
Once again I agree with you that the length of thetime is NOT an issue, rather than a positive.
I won’t re-state the arguments –you have made them all - and have done it very well.
The simple point I would put forward is this ...
Prof Parvin Kaumaya has chosen to COMBINE PD1-Vaxxwith B-Vaxx !!!
Why? Because the B-Vaxx trial is ‘open label’ andhe can see what it does and how it works (esp with HER-2).
He is not interested in ‘taking a chance’,especially when he is working with three leading cancer centresin the US.
He knows what’s going to happen. The key finds are ...
- PD1-Vaxx outperformed the standard anti-mouse PD-1 antibody (mAb 29F.1A12) in an animal model of HER-2 expressing colon carcinoma;
- The combination of PD1-Vaxx with combo HER-2 peptide vaccine (B-Vaxx) showed enhanced inhibition of tumor growth in a HER-2-positive colon cancer model;
- Both the PD-1 and the combined vaccines were safe with no evidence of toxicity or autoimmunity.
In my opinion, I think we have some amazing results coming when the B-Vaxx results are released later in the year.
Watch the share price jump then. Just my opinion, so do your own research.
You've got to love this company.
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