If not an outright success, hopefully the study will at least identify a 'sweet spot' for intervention based on inflammatory markers.
If you are feeling scientific, an article on inflammation and pain in disc degeneration. Mentions the role of cytokines in disease progression.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345483/#!po=0.276243
Check out figure 1 and table 3, for some of those familiar markers and mechanisms.
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