"The lack of mobility resulting from DDD isn't something that...

"The lack of mobility resulting from DDD isn't something that anyone can change at present. Potentially, a prosthetic disc replacement surgery could achieve this, but no one is going to risk that just to get more mobility."

That is part of what the Phase III trial is testing, below is from the product page.

"Existing therapies treat the symptoms of the disease, but are not disease-modifying and thus do not address the underlying disease cause. As a result, we believe that the most significant unmet need is a therapy that can not only improve the patient’s pain and function, but has the ability to reverse, halt or slow disease progression."

The trial is addressing both easing pain and repair.

"The ideal solution is to stimulate the brain in the same way as opioids through close relationships, good family life and purposeful work life."

Mesoblast would beg to differ.