The MAGIC Algorithm Probability (MAP) combines the serum concentrations of two biomarkers, Reg3α and ST2, into a single value that predicts long term outcomes such as response to therapy after 28 days and 6 month non-relapse mortality (NRM) (3). The MAP is an accurate monitoring biomarker of GVHD in the GI tract and is considered a “liquid biopsy” of crypt damage (4). MAPs ≥0.291 predict high NRM and poor responses to therapy in SR acute GVHD .....
https://ashpublications.org/bloodadvances/article/3/23/4034/429584/The-MAGIC-algorithm-probability-is-a-validatedThe MAGIC algorithm probability is a validated response biomarker of treatment of acute graft-versus-host disease
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