There are no motor problems in AD and this won't be an issue in...

There are no motor problems in AD and this won't be an issue in AD trial cognition executive function and life skills will be important

These HD results are a bit of a red herring and I think the AD results will be statistically significant for a number of parameters that don't include motor function

Don't forget the 83% 'satisfaction rate' that kept people on the extension trial

One could argue that the HD problems were too advanced and that PBT2 may have prevented or slowed the development of these problems if given earlier or at a higher dose

A challenge for the FDA to get more HD patients on PBT2 sooner rather than later