another piece of baseless ramping by me, so phaps a forward looking statement, look out HC readers, dont be fooled...lol
but just while the paint is drying, another spin on those phiii detailed results...
so, ATC was 14% better than 3tc when m184v and >3 tams
>3 tams are associated with significant resistance to azt, d4t, 3tc, ftc, tdf, abc and ddi
did i miss any there!?!
or in other words, just about ALL other NRTIs, except ATC and some toxic nasties, so pts left with only 2 active drugs from other classes
based on the frequency of >3 tams in phiib, that would be about 40-45% of those with m184v resistance, plus others without m184v as 3rd most common resistant mutation (ATC also active against the top 2, m184v and the nnrti mutation k103n)
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another piece of baseless ramping by me, so phaps a forward...
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