We understand the similarities between NNZ-2566 and NNZ-2591 but it is understanding the differences which will create alternative therapeutic pathways. It appears that NNZ-2591 may have a more direct effect on synaptic signalling.
Neurons do not connect with each other but communicate through a junction called a synapse. The junction is what Professor Mike Snape - http://vimeo.com/71532531 - might call the 'twitter space' where there are glia-neuron interactions, namely microglia and astrocyte.
There is a growing level of excitement about the MOA for NNZ-2591. The US Army is "characterising the impact of the drug on the restoration of synaptic function". Neuren have commenced testing NNZ-2591 in a mouse model of MS which is characterised in part by abnormal functioning of microglia.
Although the reasons are not yet fully understood, it does appear that NNZ-2591 is quite distinct from NNZ-2566. The results from the testing of NNZ-2591 in a mouse model for MS are eagerly anticipated.
- Forums
- ASX - By Stock
- NEU
- biggest competitor to nnz-2566
biggest competitor to nnz-2566
-
-
- There are more pages in this discussion • 21 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add NEU (ASX) to my watchlist
|
|||||
Last
$19.39 |
Change
-0.470(2.37%) |
Mkt cap ! $2.478B |
Open | High | Low | Value | Volume |
$19.70 | $19.77 | $19.28 | $10.38M | 534.0K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
3 | 2680 | $19.35 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$19.41 | 362 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
3 | 2680 | 19.350 |
1 | 1365 | 19.320 |
3 | 2436 | 19.310 |
2 | 4246 | 19.300 |
5 | 2474 | 19.290 |
Price($) | Vol. | No. |
---|---|---|
19.410 | 362 | 1 |
19.490 | 1365 | 1 |
19.500 | 24 | 1 |
19.520 | 1365 | 1 |
19.540 | 1180 | 2 |
Last trade - 16.10pm 30/07/2024 (20 minute delay) ? |
Featured News
NEU (ASX) Chart |
The Watchlist
MTL
MANTLE MINERALS LIMITED
Nick Poll, Executive Director
Nick Poll
Executive Director
SPONSORED BY The Market Online