Guys, there is a company called 'Frenesius' that has a BCM product, of which I found it to be less superior than Sozo (or L-Dex) as it measures only across 50 frequencies and are not able to even detect changes in impedance if you've drunk 1 litre of water. Frenesius is a $24B Euro mkt cap giant and specialise in the kidney space.
I believe that the next blue sky for Impedimed to tackle after lymphedema and Congestive Heart Failure market is in the kidney space! (note that I still think that general consumer use of Sozo is a side-income). Plenty of $$ to snatch from the giants! Obviously it's a good thing to not overspread itself upfront and tackle the first 3 markets (Lymphedema, CHF, Fitness) first, then once the company is more established, let's go for the bluer skies!
Some useful references on how BIS can be used for kidney patients as per below:
https://www.nice.org.uk/advice/mib41/chapter/references
Application of bioimpedance spectroscopy for the assessment of fluid overload, urea distribution volume and nutrition status
Cox-Reijven PL, Kooman JP, Soeters PB, van der Sande FM, Leunissen KM. Role of bioimpedance spectroscopy in assessment of body water compartments in hemodialysis patients. Am J Kidney Dis. 2001; 38: 832-838
Earthman C, Traughber D, Dobratz J, Howell W. Bioimpedance spectroscopy for clinical assessment of fluid distribution and body cell mass. Nutr Clin Pract. 2007 Aug;22(4):389-405. Review.
Fisch BJ, Spiegel DM. Assessment of excess fluid distribution in chronic hemodialysis patients using bioimpedance spectroscopy. Kidney Int 1996; 49: 1105-1109
Katzarski KS, Charra B, Laurent G et al. Multifrequency bioimpedance in assessment of dry weight in haemodialysis. Nephrol Dial Transplant 1996; 11 Suppl 2: 20-23
Kraemer M, Rode C, Wizemann V. Detection limit of methods to assess fluid status changes in dialysis patients. Kidney Int 2006; 69: 1609-1620
Lopot F, Nejedly B, Novotna H, Mackova M, Sulkova S. Age-related extracellular to total body water volume ratio (ECV/TBW) - can it be used for "dry weight" determination in dialysis patients? Application of multifrequency bioimpedance measurement. Int J Artif Org 2002;25(8):762-9.
Passauer J, Miller H, Schleser A, Leicht J, Pucalka K. Evaluation of Clinical Dry Weight Assessment in Haemodialysis Patients by Bioimpedance-Spectroscopy. Journal of the American Society of Nephrology 2007; 18: 256 A
Spiegel DM, Bashir K, Fisch B. Bioimpedance resistance ratios for the evaluation of dry weight in hemodialysis. Clin Nephrol. 2000 Feb;53(2):108-14.
Wabel P, Rode C, Chamney PW, Moissl U, Wizemann V. Lean Tissue Index Assessed with Bioimpedance Spectrsocopy is a Strong Predictor of Mortality in Hemodialysis Patients. J Am Soc Nephrol 2007; 18(2007):90 A.
Wuepper A, Tattersall J, Kraemer M, Wilkie M, Edwards L. Determination of urea distribution volume for Kt/V assessed by conductivity monitoring. Kidney Int. 2003 Dec;64(6):2262-71.
Załuska WT, Małecka T, Swatowski A, Ksiazek A. hanges of extracellular volumes measured by whole and segmental bioimpedance analysis during hemodialysis in end-stage renal disease (ESRD) patients. Ann Univ Mariae Curie Sklodowska [Med]. 2002;57(2):337-41.
