Yes, that paper describes testing them in mouse stomach. Agreed, it was not tested in the plasma. Plasma does have proteases and the complement but not to the level of digestive enzymes and proteases present in the stomach! Stomach digests everything in your food and for that reason, testing the iBodies in the stomach is kind of baptism of fire. As for production of therapeutic molecules, it is highly regulated. One of the most important costs associated with any therapeutics (other than clinical trials) is the production adhering to GMP (Good Manufacturing Practices). Contaminating proteins/endotoxins are not an issue. Insulin is produced in E. coli or in S cerevisiae and has been in use for more than half a century by diabetics world-wide (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203937/). Adalta's i-Bodies are produced in CHO cells (Chinese Hamster Ovary), which are mammalian cells with no endotoxin (unlike E. coli). For these reasons, the only impediment for Adalta's success is the human clinical trial results. IMHO
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