"..on March 16 2020, the first phase I clinical trial of a novel lipid nanoparticle (LNP)-encapsulated mRNA-based vaccine, mRNA-1273, which encodes the spike protein (S protein) of SARS-CoV-2, began in the United States (US), conducted by Moderna and the Vaccine Research Center (VRC).." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218962/
in connection with
"The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice"