Maxine, I can't find anything wrong with the science, no matter how hard I try. This is really the most advanced ddRNAi program and it is a very safe target. The only thing I can come up with is the dominance of bean counters and non-scientist financial types in Pfizer and that at the time they let it go ddRNAi was EXTREMELY unfashionable. To be in ddRNAi in a big Pharma meeting at that time would've been a bit like turning up in massive flares and a paisley shirt with sunglasses and a moustache at a business lunch. Don't underestimate the power of fashion in the drug industry!
How funny if Pfizer end up having to beg to pay royalties on this to BLT as the master!
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