I dont think its an easy fix arundpr. In an ideal glass half full world yes they should build more fat into the up fronts. In the real world they are now proving that it is near impossible to sign a deal with the current levels of upfront payment, unless of course they actually are asking for more and that is why no deals are being signed. I suspect the reason they got so many big signatures at the start was because the up fronts were so insignificant the pharmas thought the risk reward was good. Since the four initial deals have really produced nothing except an extension with janssen maybe other potential clients have lost faith. Obviously there was nothing of use in the original hyped up libraries. The new libraries with virulent samples etc may have more success but who knows
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I dont think its an easy fix arundpr. In an ideal glass half...
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