CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells, page-3

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    No worries mate! hope you find some value in it

    Also in reference to your comment able, just a reminder on cell types:
    T cells: recognise specific antigens presented by other cells and initiate a targeted immune response (adaptive immune system)
    NK cells: cells recognise and kill virus-infected cells and tumor cells without prior sensitisation (innate immune system)
    NKT cells: cells recognise lipid antigens presented by the CD1d molecule (Bridge between innate and adaptive immunity). Note, less than 0.1% of peripheral blood mononuclear cells are iNKT cells and NKT cells play a critical role in tailoring immune responses contributing to overall immune system homeostasis.

    Invariant: iNKT cells have a TCR (T-cell receptor) common to all humans. This makes the iNKT cells from other people look the same to our immune systems, creating allogeneic (donor-supplied) opportunities.
    Induced: as in iPSC cells refers to the process of reprogramming adult cells, like skin cells, to revert them to cells similar to embryonic stem cells

    Last edited by Kelvin8r: edit 14/10/24
 
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