That's true. The FDA approved dosage is 52 mg/m2 in paediatrics and 40mg/m2 in adults. Sheba 2.0 dosage was 30 mg/m2.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021673s024lbl.pdf
https://pubmed.ncbi.nlm.nih.gov/19260120/
The cardiotoxic profile of Clofarabine is (IMO) under appreciated due to the lack of data (and the lack of willingness to even report it!).
Cardioprotection thread, page-440
-
- There are more pages in this discussion • 176 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Add RAC (ASX) to my watchlist
 (20min delay)
|
|||||
|
Last
$1.70 |
Change
0.090(5.59%) |
Mkt cap ! $289.5M | |||
| Open | High | Low | Value | Volume |
| $1.60 | $1.76 | $1.59 | $142.7K | 84.97K |
Buyers (Bids)
| No. | Vol. | Price($) |
|---|---|---|
| 2 | 17175 | $1.70 |
Sellers (Offers)
| Price($) | Vol. | No. |
|---|---|---|
| $1.77 | 6060 | 1 |
View Market Depth
| Last trade - 16.10pm 05/07/2024 (20 minute delay) ? |
| RAC (ASX) Chart |