I would recommend that you consider the effects of a damaged heart on quality of life. Millions and millions of people each year are forced to make a choice that kills the cancer in their body, but significantly decreases their quality of life in the years that follow. The years of quality life lost to the successful treatment of cancer is massive. How much would you be prepared to pay for something that helped treat your cancer, but also enabled you to ride like normal long into your years? That option has never existed for patients before, however, if successful, it will be for millions that follow.
https://www.ncbi.nlm.nih.gov/books/NBK599501/
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2800936
@IAmShovel
My understanding is things like cardiovascular performance (VO2peak), heart function (LVEF, echocardiogram), and blood biomarkers for cardiac damage (troponin, BNP) can be measured. We should know more soon. VO2peak is the best measure as it captures the impact on functional impairment to the highest degree of accuracy relative to other measures.
Cardioprotection thread, page-879
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