I may be wrong, but I get the feeling you think FTO inhibitors are cardiotoxic. FTO inhibitors have only demonstrated measureable cardiotoxicity when used in combination with cardiotoxic drugs in vitro/vivo. I haven't found any evidence that demonstrates a significant increase in cardiotoxicity from a single agent FTO inhibitor/knockdown model. If the combination effects demonstrated in cell and animal models translates to additional cardiotoxicity in patients, it is bad for FTO inhibitors, but very good for us. I don't know how the FDA will handle a meaningful percentage increase in cancer therapy-related cardiac events from a new drug class.
Just going to sit here twiddling my thumbs until RAC announce the cardio MoA('s?). It must be very strong, as it has to overcome the synergy between FTO inhibition and DOX. Just imagine if it is regeneration...
- Forums
- ASX - By Stock
- Cardioprotection thread
I may be wrong, but I get the feeling you think FTO inhibitors...
- There are more pages in this discussion • 115 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add RAC (ASX) to my watchlist
(20min delay)
|
|||||
Last
$1.59 |
Change
0.020(1.27%) |
Mkt cap ! $269.7M |
Open | High | Low | Value | Volume |
$1.58 | $1.61 | $1.58 | $15.22K | 9.589K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
2 | 1521 | $1.58 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$1.60 | 100 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
2 | 1521 | 1.575 |
1 | 230 | 1.570 |
1 | 4986 | 1.565 |
2 | 5980 | 1.550 |
1 | 1303 | 1.530 |
Price($) | Vol. | No. |
---|---|---|
1.600 | 100 | 1 |
1.605 | 2362 | 1 |
1.610 | 5194 | 1 |
1.615 | 53378 | 1 |
1.650 | 5000 | 1 |
Last trade - 10.46am 06/06/2024 (20 minute delay) ? |
|
|||||
Last
$1.59 |
  |
Change
0.020 ( 1.31 %) |
|||
Open | High | Low | Volume | ||
$1.60 | $1.60 | $1.58 | 709 | ||
Last updated 11.07am 06/06/2024 ? |
Featured News
RAC (ASX) Chart |
The Watchlist
LPM
LITHIUM PLUS MINERALS LTD.
Simon Kidston, Non-Executive Director
Simon Kidston
Non-Executive Director
Previous Video
Next Video
SPONSORED BY The Market Online