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Index, I think few have grasped the significance of Mason's...

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    Index, I think few have grasped the significance of Mason's post.

    Fto inhibition significantly decreases HCM viability when dosed with cardiotoxic agents. Zan was just used in combination with a cardiotoxic agent, yet no (NONE!) cardiotoxicity was observed...

    Either one of two sceneries have occurred (IMO):

    1. Zan doesn't inhibit FTO and the 25% reduction in Clofarabine dosing was sufficient to decrease 27% LV dysfunction cases to 0%.

    2. Zan is cardioprotective.
 
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