Cell Therapy News/Articles, page-1147

Some more thoughts on ARDS with my emphasis:

In the Benzinga article SI is quoted: "Treatments using single-pathway inhibitors don’t have a chance of switching off the cytokine storm where many cytokines are responsible",

This is a stronger statement but fits with what I've learned about ARDS and what Dr Geoff Bellingan, intensive care consultant for UCLH, said that ARDS is "a heterogeneous condition and probably needs a variety of actions".

From the Wall Street Transcript: "Multiple arms of the immune system are activated, and the cytokines produced by these cells result in progressive debilitation of the heart — fibrosis — which results in hospitalizations and death".

I find it interesting that SI makes specific mention of fibrosis here as it's also very relevant to ARDS; fibrosis is a major complication of this condition. How many of the drugs being touted for ARDS. prevent fibrosis which MSCs are known to do? .

My view is that cellular medicine is the best possible match for ARDS.

Just one final thought, a few years ago I was looking into folistatin at a time when I thought surgery might not be survived. I decided this (protein?) alone was something special.for repair and I wondered recently if MSCs secrete it. and sure enough, there's a fair bit of research on this.

I'm really starting to see how MSCs will replace drugs, which is imo why the battle has been so long and fierce

All IMO. Feel free to make any corrections as I'm not a scientist