@whytee @DocMcstuffins
I distinctly recall SI saying in one webcast a few years ago MSB would be willing to run a RCT in high risk adults against something approved and therefore Ruxolitinib if that's what the FDA required.
I can't find the link now but prior to this (at least a year), I also distinctly recall an interview with KOL Dr. Susan Prockop saying that after her center's experience of treating 3 patients with Rux (She was very specific about the effects) they wouldn't be participating in a clinical trial.
Why would she say this unless she'd been asked?
I'd be grateful if you could both answer the following questions "yes" or "no"
1. Is it a fact that Dr Prockop was never asked to participate in a RCT in Ryoncil?
2. Is it your opinion that if a randomised controlled study in adults did go ahead and showed no efficacy (unlikely IMO), that would be proof it wasn't effective in children either?
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