Sufficient data was obtained to permit proceeding to Phase II Human study, i.e. a safe and active dose. The study was also terminated to permit reformulation of study drug to a more palatable formulation.
The above is an Extract from the 1st Phase I Human Trial , this was utilising a capsule of Liquid MPL. The formulation was poorly tolerated but the scientific data gained impressive.
Especially when you research the candidates ,
Male or female patients with progressing and unresectable tumours in whom all standard treatments have been exhausted or have been contraindicated.
Life expectancy of at least 3 months, in the opinion of the Investigator.\
As this application was granted previously before reformulation by BRI and the Molecule and Delivery have been enhanced a V 2.0 Phase I in Humans would be swift in replication, Phase II approval would be a given IMHO (if canines who's sense of smell and taste is far superior do not find offence in the newly formulated MPL, , Human Pills can literally be flavoured to suit)
Here is a completed application previously by Pharmaust https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=366350 only terminated early to reformulate the capsule, but still gained adequate info to be able to move on to Phase II Human Trials ,, Possibly on a close time horizon.
This confirmed Cancer Fighting abilities of MPL https://stocknessmonster.com/announcements/paa.asx-6A719064/
Must admit was hoping for a Catalyst of News to propel the SP, IMHO, the Long Term Holders that invested in that crucial CR after the poor formulation , took a heck of a punt and the Oppies would have been part of that reward...
News ,,Early in the week would be an enabler that would net the company $2.4m in company funds.. with the Options exercised.
Enjoy the weekend ,,, One week closer, one more week of progress completed....
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