Pathogenic Human Coronavirus Envelope Protein: A Clear Link to Immunopathology?
The clinical presentation of SARS and MERS is remarkably similar to COVID-19, with hyperinflammation causing a severe form of the disease in some patients. Previous studies show that the expression of the SARS-CoV E protein is associated with the hyperinflammatory response that could culminate in acute respiratory distress syndrome (ARDS), a potentially fatal complication
https://www.preprints.org/manuscript/202005.0414/v1
Although much of the focus with the global pharma market has been on the S (spike) protein with limited results for such a vast focus, I find it interesting to note that there are more and more studies/papers looking at the E-protein and Covid-2, and as BIT appears to be the only real candidate that has dedicated years on the E-Protein (with thus far encouraging results) would also suggest that BIT may be in the prime position with their BIT compounds and Covid-19.
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