Well there are a number of mining companies out there that are...

Well there are a number of mining companies out there that are very exciting and have the potential to 10x or more in next 12 months, but most of my speculative investments are ones where I hope to generate returns something like 1-2x over 12 to 18 months with what I hope is minimal downside.

It sounds like you are more a gambler than an investor. There is nothing inherently wrong with this, but it is not what the biotech industry needs. Rather than people looking for a 20x return in weeks, it needs people looking for a 10x return over 10 years.