My friend Happell, Indeed there are a number of advantages of a repurposed drug, some of which include, but perhaps not limited to:
- Faster pathway
- Don't have to do a Phase 1 (safety in humans already has been established)
- Cheaper overall as a lot of the required R&D is cut out
- Completely different therapeutics are possible utilising the same base drug
- ...and yes, the odds of success do go up
How much are our odds on average increased then? Ah a little harder to quantify but I'm hearing around 10% boost overall 2, doesn't sound like a lot but it can help.
You have to take into consideration there is still risk, tox studies are definitely vital as the route to administration can change like in our case, the bio availability (Read: uptake in body) can be a whole heap different along with things such as Mechanism of action and then various loads on other organs such as Liver, Spleen, Kidney etc.
DYOR
References Used
1) https://www.technologynetworks.com/drug-discovery/articles/drug-repurposing-advantages-and-key-approaches-344261
2) https://www.alacrita.com/blog/the-risk-reward-balance-in-drug-repurposing#:~:text=In%20theory%2C%20the%20probability%20of,at%2010%25%208%2C11.
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