Ros production is increased by Bisantrene not deceased. ROS production is a major cause of cardiotoxicity, so this confirms the theory that bisantrene self-rescues cardiotoxocity.
Source: Full article: Enhanced cytotoxicity of bisantrene when combined with venetoclax, panobinostat, decitabine and olaparib in acute myeloid leukemia cells (tandfonline.com)
Source: Comparative study of the metabolic effects of anthracendione and anthrapyrazole agents. Franks, P, 1987.
Ros production is increased by Bisantrene not deceased. ROS...
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