There are several natural edible compounds that have been...

There are several natural edible compounds that have been identified as potential inhibitors of FTO-mediated m6A demethylation. Here are some examples:

1. Curcumin: Curcumin is a polyphenol compound found in turmeric, a spice commonly used in Indian and Southeast Asian cuisine. Curcumin has been shown to inhibit FTO activity and increase m6A levels in cells, suggesting that it may have therapeutic potential in diseases associated with FTO dysregulation.
   

2. Epigallocatechin gallate (EGCG): EGCG is a flavonoid compound found in green tea. EGCG has been shown to inhibit FTO activity and increase m6A levels in cells, suggesting that it may have therapeutic potential in diseases associated with FTO dysregulation.

3. Resveratrol: Resveratrol is a polyphenol compound found in grapes, berries, and red wine. Resveratrol has been shown to inhibit FTO activity and increase m6A levels in cells, suggesting that it may have therapeutic potential in diseases associated with FTO dysregulation.

4. Quercetin: Quercetin is a flavonoid compound found in many fruits and vegetables, including apples, onions, and berries. Quercetin has been shown to inhibit FTO activity and increase m6A levels in cells, suggesting that it may have therapeutic potential in diseases associated with FTO dysregulation.

While these natural compounds show promise as potential inhibitors of FTO-mediated m6A demethylation, further research is needed to fully understand their mechanisms of action and their potential as therapeutic agents.