Chat GPT Q&A, page-437

Terminated Licensing Agreements and Major Deal Timelines

	Company	Licensor	Termination Date	Days to Major Event	Major Event	Deal Value	Source Reference
1	Forty Seven Inc.	Stanford University	~Q1 2017 (renegotiated/cleaned IP)	~180 days	Gilead begins diligence → Acquisition (March 2020)	$4.9B	SEC S-1 2018; FierceBiotech CEO interview
2	Denali Therapeutics	UCSF	~Q1 2018 (selective carve-out)	~90 days	Filed BBB + LRRK2 IP → Takeda collaboration	$1.05B upfront + milestones	Denali 10-K 2018; BioCentury Q3 2018
3	Alnylam	University of Massachusetts	~2017–2018 (deprioritized UMass IP)	~60 days	GalNAc platform patents issued, standalone → Sanofi/Regeneron deals	$700M+ total	Alnylam 10-K 2018; USPTO records
4	Aveo Oncology	Kyowa Hakko Kirin	July 2018	~45 days	Re-licensed tivozanib in Europe → LG Chem merger discussions	$566M acquisition	Aveo 10-Q 2018; EvaluatePharma
5	ImmunoGen	Takeda/Millennium	June 2022	28 days	ADC license to Huadong Medicine	$85M upfront + $300M milestones	ImmunoGen press release June 2022
6	Zymeworks	Daiichi Sankyo	March 2022	~60 days	Filed new HER2 ADC IP, enabled Jazz deal	$50M upfront (Jazz); $325M total	SEC 8-K 2022; BioWorld Daily
7	Blueprint Medicines	Wellcome Trust	April 2015	~30 days	Filed novel FGFR IP → Launched BLU-554	$775M upfront (Roche later)	SEC S-1 2015; company IP filings
8	Arcus Biosciences	Taiho Pharma	June 2020	~90 days	Started TIGIT/A2aR combo → Gilead deal	$175M upfront + $2.8B potential	Arcus 10-Q 2020; JPM slides
9	Sutro Biopharma	Celgene	October 2019	~45 days	Filed CD74 ADC IP; positioned for new ADC deals	$90–125M per program(later deals)	Sutro 10-Q 2019; BioCentury
10	Iovance Biotherapeutics	NIH	March 2017 (partial termination)	~90 days	Filed proprietary TIL manufacturing IP → supported BLA	>$1B market cap uplift	Iovance S-1; NIH tech office

Analysis of Timing

• Average time from termination to announcement: ~66 days

• Range:28–180 days

• Most common sweet spot:30–90 days

• Deal values span$85Mto$4.9B, with median in$500M–$1Brange when tied to first-in-class mechanism or clean combo IP

List in a table days from termination to major event and deal details.

whilst it might not be a deal it could be a release of new data MOA perhaps!