Good morning all
We may get an Announcement on Monday - because the Clinical Trial for CF33 CHECKvacc is now listed on the City of Hope website:
"A Phase I, First-In-Human, Open-Label, Non-Randomized, Dose-Escalating, Single-Center Phase I Study of Intratumoral Administration of CF33-HNIS-AntiPDL1, A Novel Chimeric Oncolytic Poxvirus Encoding Human Sodium Iodide Symporter (HNIS) in Patients with Metastatic Triple Negative Breast Cancer:
Source: https://oncore.coh.org/sip/SIPMain#
The TGA's IND approval was back on 2 July, and LC has previously stated that we were waiting on the City of Hope Ethics Committee for approval to proceed - so it looks like that has now happened.
This is extremely good news. The CF33 pre-clinical results were outstanding. Now we can find out what happens in patients.
This is only a Phase 1 trial, but if if CF33 really does work in humans then the results should be quite dramatic. An Oncolytic Virus will move much faster than Immunotherapy - which takes time for the body to develop the immune response. In fact Checkvacc is the best of both worlds. In pre-clinical studies the CF33 virus has been shown to be massively effective at even tiny doses - finding and destroying cancer cells. However it is also armed with an anti PDL1 immune checkpoint inhibitor - which will make the cancer cells "visible" to the immune system and opens them to attack that way as well.
The original Company announcement of the IND approval contains a bit more background on the trial: https://hotcopper.com.au/threads/ann-fda-ind-approval-of-new-oncolytic-virotherapy-checkvacc.6141869/
Good times ahead. Have a happy weekend all!
Cheers
Dave![]()
- Forums
- ASX - By Stock
- IMU
- Checkvacc Clinical Trial - now listed at City of Hope
Checkvacc Clinical Trial - now listed at City of Hope
-
-
- There are more pages in this discussion • 125 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add IMU (ASX) to my watchlist
|
|||||
Last
5.5¢ |
Change
-0.001(0.91%) |
Mkt cap ! $404.2M |
Open | High | Low | Value | Volume |
5.5¢ | 5.6¢ | 5.4¢ | $289.6K | 5.270M |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
44 | 3695171 | 5.4¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
5.5¢ | 345634 | 15 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
44 | 3698606 | 0.054 |
22 | 3717322 | 0.053 |
23 | 2152678 | 0.052 |
19 | 1503914 | 0.051 |
66 | 4425129 | 0.050 |
Price($) | Vol. | No. |
---|---|---|
0.055 | 460066 | 16 |
0.056 | 1241153 | 12 |
0.057 | 1440306 | 12 |
0.058 | 277086 | 6 |
0.059 | 637173 | 7 |
Last trade - 12.46pm 29/07/2024 (20 minute delay) ? |
Featured News
IMU (ASX) Chart |