CHM chimeric therapeutics limited

Chimeric: Media Thread, page-148

  1. 318 Posts.
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    • Sorry to hear dalts. Its a devastating disease with no real SOC.
    • Glioblastoma (or GBM) is one of the most complex, deadly, and treatment-resistant cancers.
    • More than 13,000 Americans are expected to receive a GBM diagnosis in 2020.
    • GBM accounts for 48 percent of all primary malignant brain tumors.
    • It is estimated that more than 10,000 individuals in the United States will succumb to glioblastoma every year.
    • The five-year survival rate for glioblastoma patients is only 6.8 percent, and the average length of survival for glioblastoma patients is estimated to be only 12 to 18 months.
    • Survival rates and mortality statistics for GBM have been virtually unchanged for decades.
    • Despite first being identified in the scientific literature in the 1920’s, there have only been four drugs and one device ever approved by the FDA for the treatment of glioblastoma.
    • None of these treatments have succeeded in significantly extending patient lives beyond a few extra months.
    • Some patients have a glioblastoma upon diagnosis (de novo or primary GBM), while other patients’ tumors start as another, lower-grade type of brain tumor and over time progress into a glioblastoma (secondary GBM). A vast majority of GBM diagnoses are de novo.
    • Mean age at diagnosis is 64.
    • In addition to being life-threatening, GBM – and its harsh treatments – inflict devastation upon the brain, which controls cognition, mood, behavior, and every function of every organ and body part.
    • Many patients will lose their ability to work, drive, and a host of other functions that contribute to one’s sense of self and independence.
    • Glioblastoma is also one of the more expensive cancers to treat, often leaving patients and families with major financial hardship on top of the burdens of the disease.
    • Prominent Americans who’ve been lost to this type of cancer include: Beau Biden (son of former Vice President Joe Biden, and former Attorney General for the state of Delaware); Gary Carter (Hall of Fame Major League Baseball player); U.S. Senator Edward “Ted” Kennedy (Democratic politician); U.S. Senator John McCain (Republican politician and former presidential nominee); and Edward “Tug” McGraw (Major League Baseball player and father of country music star and actor, Tim McGraw).
    • From National Brain cancer society website. 22 July is GMB awareness day.
    • Hopefully some good news for patients.
 
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