CHM chimeric therapeutics limited

There's not many tweets being posted related to CHM, Dr. Brown,...

  1. 49 Posts.
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    There's not many tweets being posted related to CHM, Dr. Brown, City of Hope, etc. but here are the ones that I've found:

    Some of them have screenshots of their presentation slides that are interesting:

    https://twitter.com/bryankli/status/1462113162161971201?s=20

    https://twitter.com/MrugalaMaciej/status/1462280664414314498?s=20

    https://twitter.com/SonikpreetA/status/1462078187169533952?s=20

    https://twitter.com/AshleySumrallMD/status/1462095267168198656?s=20
    - Actually some patient data - don't know which patient this is out of the 4 in the 1st cohort and not entirely sure how to decipher this information, but it seems like the treatment protocol is enrolment --> surgery --> CAR-T Therapy. So from this, patient UPN 487, was enrolled, had surgery, then given CLTX CAR-T. This patient never grew a tumour at the initial tumour location (left frontal lobe), but had a tumour recurrence in a distant location (left temporal lobe) 2 months later, which also expresses MMP2+, so they will now progress to dual therapy (not sure what they mean here). I'm sure the information will be clearer when we see the presentation or the poster, but from what I see, CLTX CAR-T seemed to stop tumour recurrence in the initial tumour location, but it was not able to stop recurrence in other tumour locations (not sure if the recurrent tumour in the left temporal lobe comes from the initial tumour in the left frontal lobe.) The person that posted this thread (Ashley Sumrall who is a neurooncologist - https://www.linkedin.com/in/ashley-sumrall-md-facp-0527b144/) seems to be fascinated about the information that we all know from the abstracts and announcements regarding specificity, safety, and it's early efficacy readings.

    That's all I was able to find in twitter.

 
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