My concern with the COVID-19 ARDS trial is that it is taking so long to do the enrollments. With the number of deaths in US I thought we'd see full enrollment in the first couple months. The total US death count as of October 7th for "Deaths involving COVID-19 and Pneumonia, excluding influenza" (the most likely group for ARDS and ventilator therapy in my view) is 89,981. https://www.cdc.gov/nchs/nvss/vsrr/covid19/index.htm
I remember distinctly reading something back around the time Mesoblast initiated it's COVID-19 ARDS trial that some US agency was going to coordinate the allocation of patients into the many COVID-19 trials in order to supposedly improve the overall outcomes. I wonder if there is some slow-walking going on regarding allocation of patients to the Mesoblast trial. Worse yet would be a deliberate allocation of patients with worst prognosis to trials. I guess I'm just not a trusting person these days...
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