Here's a worthwhile read:
Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial | Nature Medicine
Oncolytic Virus ? Check.
Pembro (Keytruda) Combination ? Check.
Durable responses ? Check.
Complete responses ? Check.
Median time to response, 3 months.
All very interesting and adds weight to the argument that Immunotherapy combinations with Oncolytic viruses may be effective treatments for cancer. Whilst some may see this as the competition, i prefer to look at it as real world validation that also informs the work Imugene is undertaking.
GLTAH.
Competitive landscape, page-239
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