Can anyone clarify if other TAVR makers ‘first in human’ trial related to trialing the complete TAVR valve (complete with catheter use) or involved testing the valve/leaflet portion via SAVR initially?
I’m trying to get a better understanding of the time to market for AHZ’s TAVR from now.
With little basis for my current assumption I’m guessing 5 yrs? 2yrs for SAVR, trial and outcome plus 2yrs for TAVR trial and outcome, 1yr stuffing around with trial design/patient recruitment?
Some figures below for SAVR / TAVR average device costs (and the associated benefits).
TAVR = $30k USD
SAVR = $ 5k USD
Economic Implications of Transcatheter Aortic Valve Replacement in Patients at Intermediate Surgical Risk
https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.116.021962
”TAVR may provide both high clinical and economic values in intermediate-risk patients, but final conclusions will require the completion of rigorous analysis. In addition to the aforementioned issues, this analysis may need to consider the issue of long-term valve durability. Most high-risk patients with aortic stenosis are elderly and, thus far, it has appeared unlikely that long-term valve performance would affect cost-effectiveness. Whether this is also true for younger, lower-risk patients is not yet known.”
Emphasis mine in extract above.
I guess AHZ could begin selling SAVR valves within a few years, assuming good trial results, however at $5k I doubt that would cover costs. Perhaps SAVR gets licensed for a better deal than we have see previously?
I can’t see how decent data on AHZs TAVR (potential) to produce superior quality-adjusted life-year gains could be published in less than say 10yrs from now?
I recall some surgeons had used ADAPT material to manually replace heart valve leaflets (a few? years ago) perhaps that data could be used to verify anti-calcification however I would imagine long term superiority would need to be valve against valve.
- Forums
- ASX - By Stock
- AVR
- Competitor - JenaValve
Competitor - JenaValve, page-18
-
- There are more pages in this discussion • 4 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add AVR (ASX) to my watchlist
(20min delay)
|
|||||
Last
$11.55 |
Change
-0.130(1.11%) |
Mkt cap ! $244.1M |
Open | High | Low | Value | Volume |
$11.71 | $11.89 | $11.41 | $703.3K | 60.2K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
1 | 2 | $11.55 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$11.83 | 500 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
1 | 2 | 11.550 |
1 | 1341 | 11.500 |
1 | 1000 | 11.400 |
1 | 2 | 11.260 |
1 | 8 | 11.220 |
Price($) | Vol. | No. |
---|---|---|
11.830 | 500 | 1 |
11.900 | 1000 | 1 |
12.000 | 5317 | 2 |
12.400 | 198 | 1 |
12.500 | 429 | 1 |
Last trade - 16.10pm 11/10/2024 (20 minute delay) ? |
Featured News
AVR (ASX) Chart |