Type 5 (respiratory isolation room) air-handling requirements
The supply and exhaust of Type 5 (respiratory isolation) rooms should provide a negative pressure, relative to the corridor and adjacent areas. To obtain the negative pressure, the exhaust flow rate should be a minimum of 10% greater than the supply air with all doors and openings closed.8
For a new building, air from Type 5 (respiratory isolation) rooms ideally should not be reticulated via, or to, any other ventilation system, i.e. it should be a single pass system. Air from these rooms should be exhausted directly to the outside of the building. The discharge points should be located as far as possible from air-intakes, persons and animals. It is recommended that the discharge point be positioned above the roof and at such a height and velocity that exhausted air is unlikely to re-enter the building or its ventilation system.8
Plus it is common sense that with an airborn infection/virus any type of air conditioning should be turned off and to keep the room at a slight negative pressure will normally eliminate any random infection in the room after an infected person has been there shedding the infection
