He’s been warning for two years.
• The Immuno-epidemiological Consequences Of The Mass Vaccination (Geert)
The current SC-2 pandemic is still expanding as it is a pandemic of ‘more infectious’ variants and is thus enhancing the susceptibility of vaccinees to infection (infection-enhancing antibodies) while diminishing the susceptibility of the unvaccinated (infection-mediated training of innate cell-mediated immunity). In the pre-Omicron era, we saw more infectious variants becoming dominant; however, thanks to the neutralizing antibodies, vaccinees were still protected against disease. However, with the advent of Omicron and its growing resistance to neutralizing antibodies, vaccinees became more susceptible to infection; what we are now seeing is more virulent variants becoming dominant (Omicron subvariants BA.4 and BA.5[1]).
However, thanks to the virulence-neutralizing antibodies (which are the same as those enhancing infection at the upper respiratory tract!), vaccinees were still protected against severe disease (e.g., in case of BA.1 and BA.2). I’ve no doubt, however, that with the growing resistance of BA.4 and BA.5 to the virulence-neutralizing Abs, vaccinees will now rapidly become more susceptible to virulence. Due to repetitive activation of the immune system in C-19 vaccinees, several infectious diseases can now be spread asymptomatically by vaccinees. Due to widespread asymptomatic transmission in highly vaccinated countries and the subsequent rise in infectious pressure, infection-mediated immunity in certain subsets of the population no longer suffices to prevent productive infection.
This is now basically igniting the global spread of a number of acute, self-limiting microbial infections (e.g., ‘seasonal’ Flu, RSV but also vaccine-preventable viral and bacterial infections in countries that interrupted their childhood vax program due to Covid crisis) and also of some acute, self-limiting viral diseases (e.g., monkeypox, pandemic [avian H5N1] flu). In addition, depletion of cytotoxic CD8 T cells due to repetitive cycles of re-infection has also led to an increased recurrence/reactivation rate of chronic infections (e.g., herpetic diseases + CMV, EBV, CMV, HIV, tuberculosis..) and relapse or metastasis of certain cancers in vaccinees. In the summary appended, I am sharing my informed predictions on the health impact these pandemics will entail in different subgroups of a highly vaccinated population.
While these new pandemics are developing, the super C-19 pandemic I’ve been warning about is coming our way soon. In highly vaccinated countries, it will definitely overhaul the pandemics mentioned above. This is because massive replacement of ‘natural infection-acquired’ immunity to SC-2 by ‘imperfect’ vaccine-induced immunity is now driving the evolution of the C-19 pandemic in highly vaccinated countries. This will not be the case in poorly vaccinated countries where natural immunity has been largely preserved and the population is often much younger (e.g., African countries). Last, I’d like to repeat my advice: If you’re C-19 vaccinated: Make sure you’ve access to antivirals and antibiotics and that you’ve established a contact with an MD you can trust.
