"Data shows that E is involved in critical aspects of the viral life cycle and that CoVs lacking E make promising vaccine candidates.""During the replication cycle, E is abundantly expressed inside the infected cell, but only a small portion is incorporated into the virion envelope [65]. The majority of the protein is localised at the site of intracellular trafficking...where it participates in CoV assembly and budding"
At the risk of starting another Biotron Vs Vaccine kerfuffle...To make a vaccine using E Protein compromised Covid-19 viruses requires an agent to damage or neutralise the E protein.
Perhaps we should be looking for labs using this approach to create a vaccine. We might just find BIT preparing to provide E neutralised raw materials. Someone has to make them, and who else is so advanced in this particular area?
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