CYP Price Target post MSB FDA approval., page-101

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JB1975

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21/12/24

17:25

Post #: 77149648
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Originally posted by JB1975: ↑

I share your respect for Caplan,

He was wrong then and he’s since passed away. He knew what he was talking about and his understanding would outstrip yours.

I don't think either or he or I would say to you that science is about the size of one's ego - I think he and I would say to you (or to anyone doing comparisons of expertise)- think for yourself - do the science reasoning yourself.

The FDA now agree with him.The Marks/Verdun version of the FDA have granted MSB a BLA - that is a fact.

Why they did - that is a matter if conjecture for me - the science stuff really isn't much.

Pfeifer said he thought this a political decision not scientific one. That is also what I think.

Pfeifers said re the FDA - it was about saving face (actually this saving face stuff he and I have misunderstood each other about before - actually he thought I was referring to him when I wasn't when I said there was no need to save face (I meant the FDA hadn't lost any with the CRLs - they'd done the right thing).

Now I think its not whether the FDA under Marks and Verdun have saved face for me - its about whether or not weak politic types have sold out their souls and their duty if I could put it that way.

Please understand I am not asserting that I know for sure that Marks and Verdun did the wrong thing (on the science evaluation - not dealing with the potency assay and confounding in the GVHD001 trial transparently (perhaps they've addressed it behind the scences) because they are weak - but I am saying that that is a working hypotheis of mine - that is I'm thinking its possible Verdun and Marks failed in their duty because they are weak characters that need the approval of others and want to be a part of something big even if the something big isn't ready.

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https://www,advisory.com/daily0briefing/2024/06/25/sarepta-approval
(typing not cut and pasting) - article I'm linking to is headed
"Inside the controversy over FDA's recent gene theraoy approval"
Date June 25,2924.

I'm not looking for a discussion on this really - just posting something I read a while ago and reread when I saw Verdun and Marks making comments on the FDA approval about MSB.

CYP Price at posting: 20.0¢ Sentiment: Sell Disclosure: Held
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