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This paper was published in January - Clinical applications of...

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    This paper was published in January - Clinical applications of acellular dermal matrices: A review.

    The review is limited to English language articles published from 1999 to 2020.

    The review highlights the fact that, while use of dermal matrices was originally limited to severe burns, usage has spread to an increasing number of surgical subspecialties and procedures.

    Below is a summary of the clinical applications of dermal matrix covered in the review. No mention of stents.


    Burns

    Wound Care

    DFUs
    VLUs
    Axillary and cubital joint dermis wounds
    Tumour resection surgery
    Radial forearm flap donor site closure

    Abdominal wall/hernia

    Breast Reconstruction

    Orthopaedic

    Achilles tendon repair
    Foot/ankle arthroplasty
    Rotator cuff repair
    Glenoid resurfacing
    Forearm/Hand/Wrist - trapeziometacarpal osteoarthritis, Dupuytren’s disease, postoperative and post-traumatic neuropathic wrist pain, ligament reconstruction in arthritic hands.
    Hip and pelvis – augmentation of gluteus medius and minimus repairs, filling of capsular defects to create hip stability in hip reconstructions

    Craniofacial surgery
    Scalp coverage
    Spacer graft for upper eyelid retraction procedures
    Management of nasal lining deficiency in Le Fort 1 osteotomy

    Andrology
    Penile girth enhancement and augmentation

    Gynaecology and gynaecological oncology
    Vaginoplasty
    Pelvic cavity support and volume improvement

    Otolaryngology, oral surgery
    Gingival recession
    Regeneration of bone/soft tissue in dental implants

    Otolaryngology/ear, nose and throat (ENT)
    Laryngotracheal and pharyngeal reconstruction

    I was amused by the discussion towards the end of the article of how ethical restraints need to be considered in choice of dermal matrix. The authors note that Jewish and Islamic dietary restrictions may or may not translate to tissue implantation; Buddhists and Seventh-day Adventists are often vegan, which could lead them to refuse any animal-derived tissue products; some Hindus and Sikhs are opposed to all human and animal-derived products, whereas other Hindus allow the use of donated human tissues.

    So much simpler to stick to use of a synthetic dermal matrix!

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8785275/
 
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