POH Deals fully funded by partners:1) Insulin AnimalNovartis...

POH Deals fully funded by partners:

1) Insulin Animal
Novartis Animal Health
Deal March 2010
Ongoing
Initial payment, milestone, royalties if products utilised

2) Vaccines(Large Proteins)
CSL
Deal June 2009
Ongoing
Option, milestone, royalties - if products produced

3) Dermatitis/Psoriasis Topical Steroid
US Dermatology Company(undisclosed)
Deal Q1 2010
Phase 1 started Q2 2011
If option to license is taken will fully fund to registration as topical drug.
Milestone and royalty payments.

4) Acne
Major Global Dermatology Company(undisclosed)
(Bayer, Galderma, GSK, Novartis, Merck, Sanofi-Aventis, J&J)
Started April 2010
Clinical trial starting Q4 2011

5) Mastitis
Mastitis Management Australia
Deal Feb 2011
License Aust/New Zealand
Available Q4 2011

6) Cosmetics
Le Metier
Deal July 2009
50/50 profit share
2 products released early 2010
10 products available Q3 onwards

7) Shampoo(delivery of actives into scalp)
Rodney Cutler
Deal April 2011
Product release Q1 2012 US, UK, Australia
Royalties

8) Cosmetics-
Global Cosmetics Company(undisclosed)
Deal Q1 2010
?????

9) Over the Counter
Phusion Labortories
Deal March 2010
50/50 Joint venture with ProPhase(formerly Quigley)
10% ownership of Prophase
$1 million upfront
Launch 2012


POH self-funded commercial projects:

1) Cosmetics
Elixia ranges (12 products)
Asia, US, Australia
Includes proven fat burning cellulite cream peptide AOD9604 exclusively

2) Supplements
International Specialty Products (ISP)
Vital ET

3) Pain - Oxycodone(opioid)
Oxycodone 1 and 7 day Patch
3M doing commercial production
First and only oxycodone patch
Major anti abuse properties(abuse is a massive problem)
Phase 2/3 trials Q4
FDA approval 2012


POH projects being shopped around:

1) Insulin Human -
Basal Insulin
First and only to get insulin through the skin and by patch.
Phase 2 trial successful - Jan 2009

2) Pain/anaesthetic Lidocaine
Topical Lidocaine
5 times more effective than non TPM lidocaine
Phase 1 successfully completed Dec 2008

3) Pain - Diclofenac(anti inflammatory)
Diclofenac(Voltaren)
Phase 1 trial successfully completed Feb 2009
4 times more effective than non TPM Voltaren
treatment for Actinic Keratosis proof of concept Q3 2011

4) Supplements Animal Feed
Increases the benefits of vitamins and trace elements for animal health

5) Mastitis Global
Improves the cows natural resistance to mastitis
Enables cows to be brought back into milk production and health
15% of all cows worldwide at any time suffer mastitis

6) Supplements Vitamin D
Deficiency of Vitamin D cause many health issues
People in temperate climates have deficiency due to lack of sun exposure

7) Supplements Dietary supplements
Significantly improved oral bioavailability, absorption and efficiency of vitamins/nutrients

8) Supplements Functional foods
Significantly improved oral bioavailability, absorption and efficiency of vitamins/nutrients in foods

9) Pain - Morphine(opiod)
phase 2 trial success Q4 2006

10) Pain - Oxycodone Topical Gel
Oxycodone
Proof of concept for localised pain Q3 2011

11) Pain - Diclofenac
Diclofenac
treatment for Actinic Keratosis proof of concept Q3 2011

**The Matrix patch being used for the Oxycodone project is suitable for all opioid pain medications

We don't need steak knives............13c

Cheers Tangentland