Cancer Immunotherapies are a rapidly crowded space. The air is...

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    Cancer Immunotherapies are a rapidly crowded space. The air is sucked out of the room by the half dozen or so first-in-class PD1, PDL1 products (~$45Bn 2024). Every other approved product is essentially a me-too, scratching for the leftovers.

    Getting a first-line approval in this environment is near impossible, unless you have the next meaningful scientific discovery. Most, like IMU, are chipping round the edges. IMO, the only realistic routes for most in-development cancer treatments is in small underserved indications (bile duct is one example), modulating/combination therapy with one of the above, adjuvant therapy or, as you suggest, salvage therapy.

    Its not a bad market opportunity, just not massive.
 
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