Recell primarily focuses on regenerating the epidermal layer of...

Recell primarily focuses on regenerating the epidermal layer of the skin. However, for full-thickness skin injuries, which involve both the epidermis and the dermis, treatment often requires a more comprehensive approach that addresses the deeper dermal layer before applying the Recell spray.

For the dermis layer, treatments may include:

1. Dermal Regenerations Templates: These are bi-layered or single-layered synthetic or biological matrices that act as scaffolds to facilitate the regeneration of the dermal layer. Products like Integra™ Dermal Regeneration Template and Matriderm® are examples of such templates that provide a structure for dermal regeneration. They are applied to the wound to help in the formation of a new dermis, onto which the Recell spray can then be applied to regenerate the epidermis.

2. Skin Grafts: In some cases, especially for very deep or extensive full-thickness wounds, a skin graft may be necessary to cover the dermis. This can be an autograft (using the patient's own skin from another site), an allograft (skin from a donor), or a xenograft (skin from another species, often temporarily used). Once the graft is in place and stable, Recell can be used to enhance the regeneration of the epidermis and improve the aesthetic and functional outcomes by promoting the growth of a new, healthy layer of skin that matches the patient's natural skin color and texture.

3. Negative Pressure Wound Therapy (NPWT): While not directly used for dermal regeneration, NPWT can prepare the wound bed for either of the above treatments by promoting the removal of exudate and potentially increasing blood flow to the area. This can enhance the healing environment, making it more conducive for the application of a dermal scaffold or skin graft, followed by the Recell treatment.

By addressing the dermis with these methods, the foundation is laid for the successful application of Recell to regenerate the epidermal layer, leading to more comprehensive and effective healing of full-thickness skin injuries.

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