Hi Singhgu,
I pretty much know who you would be replying to lol!
There were 3 clinical indications chosen INITIALLY following Ph2A. FSGS, & then DKD & IgAN. It was never FSGS vs IgAN.
It was decided that DKD be run in the Ph2b with N=40 on the trial. The poster on that was presented at ASN Conference, considering this was the majority of responders on Ph2A & IgAN >50% reduction in Proteinuria on that trial. That was ON TOP of SOC (ARB). They were going for a pretty high bar there in CKD with 50% Proteinuria reduction above SOC in those endpoints at the time. Now 40% seems to be that bar & a change with surrogate endpoints on CKD trials, (see previous posts/links).
Information is out there, but might take a little time to find that trial ended in 2017.
See the the problem is when someone acts like a pigeon, asks for information & then you feed it, just uses that to attempt to sh** all over your outdoor chessboard or investment, then you have to stop & let them find their own means of finding food or fodder & hope the volume of faeces will stop.
I’m not going to be used as someone’s unpaid research assistant because they are too lazy to find that themselves & then sh** on others here from any information you do give.
This one’s writing up a research article on DXB remember, finding every negative thing he can right now, so go for it…get the breadcrumbs we drop & feed your pigeon mentality, clucking around after your mates.
Rare Disease & Orphan Status…Attractive to BP, potentially Accelerated Approval now for Orphan CKD indications 1/2 way through a single Ph3 is known.
We have big upcoming catalyst/s in this trial & it’s not your average Ph3. I’m surprised we don’t have more of these information/soul sucking predatory type posters yet. Wait til the end of Feb/early March lol.
Have a great day
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