Once all the countries are approved for the trial, and the centres are all up to speed, there will be over 80 sites recruiting.
An average of ~12 patients per centre.
Keep in mind that Prima's own estimate of their market is 3300 per ann.
They're recruiting nearly a 1/3 of that for this trial. It's a big ask, but we'll just have to be patient...
I was forwarded an email from Prima in August, which stated there was no shortage of interest in the trial from both patients and physicians.
However, they are taking their time (quite rightly) in scaling up to an 800 patient study to ensure each centre is compliant with CVac's manufacturing process. It's very important to the integrity of the data.
You can appreciate the scale involved in educating over 80 centres in more than a dozen countries.
So, as more come online, we should see accelerated recruitment.
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