As far as I know we're at a stage where we do not rely on the actual plants any more? Instead plant derived engineered cell lines are used? Whatever that means for production volumes I don't know.
"...We screened for FGF5 inhibitory efficacy via a novel 2-step in vitro pipeline consisting of an engineered FGF5 responsive cell line, followed by an activated dermal papillae (DP) cell method."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338843/
Announcement:
http://www.cellmid.com.au/SiteMedia/W3SVC921/Uploads/Documents/1651635.pdf
"Advangen’s scientists discovered potent FGF5 inhibitory activity amongst select members of the monoterpene family with the lead molecule MTP3 nearly seven times more potent than the company’s previously published inhibitors (p=0.0024)."
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