The treatment costs of Mary Millard for her insurance 1.8 million USD Out of pocket 78,000 USD (100 X-Rays, 9 Additional Surgical Procedures, 32 CT Scans, 21 ECHO's, 110 blood draws and 10 cultures, 39 ER visits, 7 re-hospitalizations....and still counting!)
I would consider the key message is that the major impact is not only the sepsis itself but all the subsequent treatments and complications that follow; it currently really appears to be a never endings story with the hope that the treatment for sepsis (flooding of body my antibiotics etc..) does not lead to other major illnesses. In addition, you see how clueless the medical community currently is regarding sepsis, they throw everything they have at it, hoping that one of the countless measures does any good. Thomad Heymann:
1.7 million cases each year in the US / 47-50 million globally (1 in 5 deaths, 25%!) 350k adult deaths each year in the US / 11 million globally Sepsis Nr.1 cause of deaths in US hospitals Sepsis Nr.1 cost of hospital and skilled nursing care 62 billion / year Sepsis leading fatal complication from Covid 19 More people die of cancer than sepsis Leading cause of death in children
Sepsis Nr.1 cause of hospital readmissions (US data) 50% of cases have lasting effects (US data) 14k amputations every year (US data) Underserved communities (Black and other "nonwhite" individuals) nearly twice the incidence of sepsis as white individuals (US data)
Main Challenges: -Low Sepsis Awareness -Poor Clinical Preparedness -Antimicrobial Resistance (AMR) -Diagnose Uncertainty -Barriers to Innovation -Lack of Coordinated Response James Graham:
Most information presented is already available in the latest corporate presentation.
Just some short comments to the Sepsis Phase 1 trial: 1 -2 higher doses to follow (above the 4,000 mg) and safety ceiling should be reached in one of these next doses. Based on the obtained ceiling they can establish a therapeutic window for treatment of sepsis (quote 49:00 "we will find that ceiling because then we can look to what is the therapeutic window where efficacy exists which we could be extremely confident exists well below these dose parameters we have here")
RCE Price at posting:
84.0¢ Sentiment: Buy Disclosure: Held
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