compunds showing activity in 2003 is obsolete in 2021 unless more reengineering and rediscovery is done. How can they get commercial deals with compunds becoming rapidly obsolete? Their rediscovery takes time for them to claim something aftet the end of COVID19, and after the end of the COVID 19, they can announce that compounds show activity, which will be their refernces in the reproduction of future announcements. While MM can do paraphrasing to adjust annoucements, compounds cannot do self-adjustments.
Fast spreading Variant, Mutation, Resistant and New Strain, page-21
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