That's certainly within the realm of play Jock , sometimes it's not "what Big Pharma may gain" but "What Big Pharma Might Lose" by not taking up a New Treatment..
Pfizer is pulling $1.2B p/a currently from Riluzole and that Drug has "Significant Adverse Effects"
From The FDA Site ,,,
Remember this is an FDA Approved Treatment.."$1.2B"Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
- Bladder pain
- bloody or cloudy urine
- blurred vision
- chills
- cough
- dark urine
- diarrhea
- difficult, burning, or painful urination
- fast, pounding, or irregular heartbeat or pulse
- fever
- frequent urge to urinate
- general feeling of discomfort or illness
- headache
- increased cough
- itching skin
- joint pain
- loss of appetite
- lower back or side pain
- muscle aches and pains
- nausea
- nervousness
- persistent loss of appetite or weight loss
- pounding in the ears
- right upper quadrant tenderness
- runny nose
- shivering
- slow heartbeat
- sore throat
- trouble sleeping
- unusual tiredness or weakness
- vomiting
- yellow eyes or skin
Incidence not known
- Black, tarry, stools
- decreased frequency or amount of urine
- difficult breathing
- increased thirst
- nausea
- pale skin
- swelling of the face, fingers, or lower legs
- ulcers, sores, or white spots in the mouth
- unusual bleeding or bruising
- weight gain
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Agitation
- back pain
- bluish-colored lips, fingernails, or palms
- blurred vision
- coma
- confusion
- dark urine
- difficulty breathing
- dizziness or lightheadedness
- drowsiness
- fever
- headache
- irritability
- memory loss
- pale skin
- rapid heart rate
- seeing, hearing, or feeling things that are not there
- seizures
- sore throat
- stiff neck
- unusual bleeding or bruising
- unusual tiredness or weakness
- vomiting
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- lack or loss of strength
Less common
- Difficulty moving
- dizziness or lightheadedness
- dry mouth
- excess air or gas in the stomach or bowels
- feeling of constant movement of self or surroundings
- full feeling
- muscle stiffness
- passing gas
- rapid weight gain
- sensation of spinning
- skin rash, encrusted, scaly and oozing
- sleepiness or unusual drowsiness
- stomach pain
- tingling of the hands or feet
- unusual weight gain or loss
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
MPL Adverse effects listed Below.....................................
MPL for the Treatment of MND 
(20min delay)