Hi Mozzarc,
Thanks for the posts.
Now, obviously this is just a chat room, and anyone can say anything they want, as they frequently do....
But with respect, however, to opine with such confidence on the highly complex subjects of a) the difficulty or otherwise of reverse engineering a bio pharma drug that was first developed more than sixty years ago, and b) the solidity, or otherwise, of PAR's IP around the treatment of bone marrow lesions with PPS, and to what extent this will serve to exclude competitors from the market, you would need, I think, as a minimum, a PhD in pharmaceutical chemistry, and a team of similarly qualified people to support you, and also a second PhD in international intellectual property law, specialising, and with extensive experience, in the pharmaceutical sector. You would also obviously need an intimate knowledge of all Bene's manufacturing processes, all fully documented, and complete visibility of all PAR's legal advice relating to its exclusive supply agreement(s), and its patent registrations, and probably a bunch of other stuff too.
Merely to assert that 'it's (all) watertight and robust' seems to be an assertion of expertise that is not necessarily well founded, and credibly to refute legitimate questions around these important matters, we would need I suggest, to do more than refer the questioner to the company's website, or say that someone knew someone else, who had recently spoken to someone, who said that the MD said everything's fine, and not to worry about it.
Also, in some cases what you are saying is, shall we say, well, a bit wrong actually. For example, generic Pentosan is actually manufactured all over the world, albeit (officially) for veterinary use, and has been for years, so it can't be that hard, can it? Or can it? Who knows? Not me, and not you either I suggest. And iPPS, by the way, is just Pentosan + H2O + not much else; no patents on it at all.
In my personal view, which I freely admit is almost wholly uninformed, I would think it quite likely that the reason nobody's produced an FDA approved version of PPS, is simply because there hasn't to date been sufficient demand to make it worthwhile incurring the trouble and expense.
This may change....remember; governments love generics, and do all they can to support them.
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