fillerina, page-45

For anyone interested in a comparison of the science behind Fillerina (topical) with Botox (injectable) as filler competitors in the anti-aging skincare market.

Comparing the descriptions in the last two paragraphs in particular, dislike of injections might not be the only reason why Fillerina should be the natural choice.

Fillerina has just one main ingredient. It is a combination of multiple different forms of the simple chemical hyaluronic acid, and there are no other active additives in their formula.
Hyaluronic Acid: A naturally occurring chemical in the body that is an important part of a number of biological processes.
Hyaluronic acid is found in our joint tissue, where it helps cushion the impact of our movements. It is found in our eyes and helps to keep them lubricated, it reduces inflammation, and it is an important part of the collagen generation and skin reconstruction functions of the skin.
Hyaluronic acid is a key piece in the synthesis of the biological scaffolds that our skin cells are constructed upon. They help with granulation, cell migration, reepithelization, and remodeling – the basic steps of wound healing and new tissue creation.
Recently there has been a wave of injectable hyaluronic acid treatments that have become popular as a cosmetic filler. They can have a plumping effect on the skin, however it is also possible that the injections can lead to severed nerve vessels and granulomatous foreign body reaction,
Because of these negative reactions associated with the injecting of hyaluronic acid, Fillerina was developed as a topical alternative. There are no reports of negative side effects related to the use of non-injected hyaluronic acid, as the body tends to recognize it as a familiar chemical.

Botox:The injection of Botulinum Toxin, commonly known as Botox, has become very popular for reducing wrinkles and rejuvenating the aging face. The effects are only temporary, but the injections can be done quickly, require no recovery time, and are not as complicated as many other cosmetic procedures for the face.
Botulinum toxin is produced by Clostridium botulinum bacteria. When a small amount of Botox is injected into a muscle, it blocks nerve signals that tell your muscles to contract. The effect is that it temporarily weakens or paralyzes the facial muscles and smooths or eliminates wrinkles in the skin for a few months.

Botulinium Toxin: A toxin produced by the bacterium Clostridium botulinum that is the most poisonous biological substance known. Botulinum toxin acts as a neurotoxin. It binds to the nerve ending at the point where the nerve joins a muscle, blocking the release by the nerve of the chemical acetylcholine (the principal neurotransmitter at the neuromuscular junction), preventing the muscle from contracting. The result is weakness and paralysis of the muscle. The muscle atrophies. The blockage of acetylcholine release is irreversible. Function can be recovered by the sprouting of nerve terminals and the formation of new synaptic contacts, which usually takes 2 to 3 months.
Very small amounts of botulinum toxin can cause botulism in one of two ways...