Beech, nuts is right. It is also very common that the control group members leave trials to try other treatments/ trials and therefore unlikely to be why the cause of any delay of the interim 2b data.
When an open trial is proving to have strong initial results within the treatment group it is unethical not to give late stage patients in the control group the same treatment, which is what herro has mentioned above.
food for thought, page-10
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